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Services

Transcriptome Analysis

Epigenomics

Genomics

From the beginning of SARS-CoV 2 (COVID 19) pandemic, Functional Genomics Core and Prisma Health Department of Internal Medicine (Chair Dr. Albreht) start testing Prisma Health Care Professionals, to monitor the epidemiological situation and improve personal wellbeing. The Core purified viral RNA from nasopharyngeal swab and spit (saliva and sputum) samples and determined the virus load in the samples by RT-qPCR and LAMP isothermal amplification. To determine virus evolution and transmission routes, we are sequencing virus genomes from positive samples.  Now, to support research and community projects, FGC offers virus detection and sequencing services to fight the pandemic.

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The FGC lab is not CLIA certified. The tests are for research projects only. 

 

COBRE Center for Targeted Therapeutics

 The COBRE Center for Targeted Therapeutics (CTT) was created to attract and foster the   professional development of talented junior scientists who are motivated to make a   difference in the treatment of debilitating diseases.

Collaborative Research

 Targeted therapeutics is research that seeks to develop new and more effective classes of   drugs against various diseases by aiming these drugs at molecular and cellular targets   that play a key role in the disease. This topic was chosen because of its societal impact,   the emergence of common technologies driving therapeutics research in different disease   areas and the presence of a critical core of senior faculty with broad acumen and   transdisciplinary vision in targeted therapeutics.

Resource Cores

 The Center for Targeted Therapeutics includes three resource cores including   the Functional Genomics Core, the Drug Design and Synthesis Core and the Microscopy   and Flow Cytometry Core .

Functional Genomics Core

 The Functional Genomics Core Facility offers state-of-the-art resources and solutions for   conducting genomics, transcriptomics, epigenomics and functional genomics projects. 

 FGC works with researchers to determine project goals and design custom solutions. FGC   assists at all stages of the projects, from support in grant development to generation of   publication-quality data.

 Transcriptome

Analysis:

From RNA purification to data analysis:

 

RNA-seq

 

Microarrays

 

RT-PCR, QPCR

 

small RNAs, miRNAs

 

mRNAs, PolyA, 

 

Ribo-zero, 

Custom assays design

 Transcriptome

Analysis:

From RNA purification to data analysis:

RNA-seqA

small-RNA-seq

 

Illumina sequencing

RNA-seq library

PolyA, Ribo-Zero

Microarrays

RT-PCR, QPCR, 

primers design, 

Custom applications

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